We will introduce the serious harm regarding the fact that diabetic patients smoke below:
Incompletely burned tobacco can generate toxic and hazardous substances, mainly including nicotine, carbon monoxide and tar. These substances have a great impact on the health of patients with diabetic foot.
For diabetic patients, smoking is considered as a chronic suicide, since they are more susceptible to various infections, which may easily run out of control considering their lower poor immunity. Smoking will reduce the barrier function of respiratory tract and cause respiratory infection, which aggravate patient's condition.
Smoking can elevate C-LDL (Low Density Lipoprotein Cholesterol) and make it prone to oxidation, and oxidized C-LDL is the main material that damages blood vessels.
Nornicotine, another natural component in tobacco, may cause vasoconstriction and vasospasm and result in blood supply reduction, tissue ischemia and hypoxia, thus aggravating the condition of diabetic foot. Healing of foot ulcers requires adequate oxygen and nutrients. Impeding blood circulation, these components in tobacco can aggravate the condition of patients with diabetic foot and exacerbate vascular and neurological diseases at the same time.
Long-term smoking can easily lead to the increase in bad cholesterols that damage blood vessels, such as blood total cholesterol, triglyceride, LDL, etc. However, those diabetic patients tend to have the abnormality of decreased good cholesterol (HDL cholesterol), which would be worse in the case of smoking and then cause vasoconstriction, thickening of vascular wall, luminal stenosis and slow blood flow. Similarly, poor blood circulation can exert great impact on patients with diabetic foot.
Carbon monoxide produced by smoking will bind to hemoglobin and form carboxyhemoglobin, which can affect the oxygen carrying capacity of red blood cells and result in tissue ischemia, hypoxia, as well as increased blood viscosity. Smoking may also induce the elevation of plasma fibrinogen, as a result, the highly possible blood coagulation will then form thrombosis. These substances greatly affect on the health of patients with diabetic foot.
Nicotine in tobacco may increase the blood glucose of serious diabetes patients and further lead to severe pancreatic injury. Tobacco can decrease the utilization of insulin in organism, so 20% -30% more of insulin is required in order to control the blood glucose.
Smoking can significantly increase the incidence of diabetic nephropathy. Diabetic nephropathy acts as both one of the most serious complications and an important cause leading to death.
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